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Elucidating the Role of microRNAs in Cancer Through Data Mining Techniques

Authors :
Alfredo Ferro
Luciano Cascione
Alfredo Pulvirenti
Alessandro Laganà
Rosalba Giugno
Giuseppe Pigola
Dario Veneziano
Source :
Advances in Experimental Medicine and Biology ISBN: 9789400755895
Publication Year :
2012
Publisher :
Springer Netherlands, 2012.

Abstract

microRNAs (miRNAs) have been shown to play a crucial role in the most important biological processes and their dysregulation has been connected to a variety of diseases, including cancer. The number of computational tools for the analysis of miRNA related data is continuously increasing. They range from simple look-up resources to more sophisticated tools for functional analysis of miRNAs. These systems may help to investigate the role of miRNAs in key biological processes and their involvement in diseases. The ultimate goal is to allow the development of regulatory models describing complex processes and the effects of their dysregulation.

Details

ISBN :
978-94-007-5589-5
ISBNs :
9789400755895
Database :
OpenAIRE
Journal :
Advances in Experimental Medicine and Biology ISBN: 9789400755895
Accession number :
edsair.doi.dedup.....b6b5c9c39d49a0b87a40245b3c0e363e
Full Text :
https://doi.org/10.1007/978-94-007-5590-1_15