Back to Search
Start Over
Impaired platelet reactivity in patients with septic shock: a proof-of-concept study
- Source :
- Platelets. 31:652-660
- Publication Year :
- 2019
- Publisher :
- Informa UK Limited, 2019.
-
Abstract
- Coagulation disorders and thrombocytopenia are common in patients with septic shock, but only few studies have focused on platelet variables beyond platelet count. The aim of this study was to evaluate whether platelets reactivity predicts sepsis-induced thrombocytopenia in patients with septic shock. We therefore enrolled consecutive patients with septic shock and platelets count >150*103/μL on the day of the diagnosis. Platelets reactivity tests were performed daily from the diagnosis of septic shock until day five; platelet volume distribution and mean platelet volume were also recorded daily. Sepsis-induced thrombocytopenia was defined as a platelet count
- Subjects :
- platelet reactivity
Blood Platelets
Male
0301 basic medicine
medicine.medical_specialty
thrombocytopenia
Pilot Projects
030204 cardiovascular system & hematology
Proof of Concept Study
Gastroenterology
NO
Critical care
Septic shock
disseminated intravascular coagulation
sepsis
Sepsis
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Humans
Distribution (pharmacology)
Platelet
In patient
Mean platelet volume
Coagulation Disorder
Aged
Disseminated intravascular coagulation
Platelet Count
business.industry
Hematology
General Medicine
Blood Coagulation Disorders
Middle Aged
medicine.disease
Shock, Septic
030104 developmental biology
Female
business
Subjects
Details
- ISSN :
- 13691635 and 09537104
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Platelets
- Accession number :
- edsair.doi.dedup.....b6a22a65af01a26258ce3002be88492c