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The rates of Cu(ii)-ATCUN complex formation. Why so slow?

Authors :
Radosław Kotuniak
Paulina Szczerba
Dobromiła Sudzik
Marc J. F. Strampraad
Peter-Leon Hagedoorn
Wojciech Bal
Source :
Dalton Transactions: the international journal for inorganic, organometallic and bioinorganic chemistry. 51(46)
Publication Year :
2022

Abstract

We used a series of modified/substituted GGH analogues to investigate the kinetics of Cu(ii) binding to ACTUN peptides. Rules for rate modulation by 1st and 2nd sphere interactions were established, providing crucial insight into elucidation of the reaction mechanism and its contribution to biological copper transport.

Details

Language :
English
ISSN :
14779226
Volume :
51
Issue :
46
Database :
OpenAIRE
Journal :
Dalton Transactions: the international journal for inorganic, organometallic and bioinorganic chemistry
Accession number :
edsair.doi.dedup.....b684ead2f97f37ea542ef98047701847
Full Text :
https://doi.org/10.1039/d2dt02856e