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Global Bounded Classical Solutions for a Gradient-Driven Mathematical Model of Antiangiogenesis in Tumor Growth

Authors :
Bo Lu
Xiaofei Yang
Source :
Mathematical Problems in Engineering, Vol 2020 (2020)
Publication Year :
2020
Publisher :
Hindawi, 2020.

Abstract

In this paper, we consider a gradient-driven mathematical model of antiangiogenesis in tumor growth. In the model, the movement of endothelial cells is governed by diffusion of themselves and chemotaxis in response to gradients of tumor angiogenic factors and angiostatin. The concentration of tumor angiogenic factors and angiostatin is assumed to diffuse and decay. The resulting system consists of three parabolic partial differential equations. In the present paper, we study the global existence and boundedness of classical solutions of the system under homogeneous Neumann boundary conditions.

Details

Language :
English
ISSN :
1024123X
Database :
OpenAIRE
Journal :
Mathematical Problems in Engineering
Accession number :
edsair.doi.dedup.....b611fc74fa118692733e9859011e8b62
Full Text :
https://doi.org/10.1155/2020/9708201