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Fumaric acid: production and separation
- Source :
- Biotechnology Letters. 41:47-57
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- Fumaric acid is a valuable compound used in foods, beverages, detergents, animal feed, pharmaceuticals and miscellaneous industrial products. It is produced on a large scale by the petrochemical route but the current tendency is towards implementing "green production" and environmental friendly technologies like biotechnological production of fumaric acid using low-cost raw materials. In this context, numerous studies focus on improving the fermentation process not only by using renewable raw material and genetically modified microorganisms, but also by developing and applying different downstream techniques for easy recovery of fumaric acid from the fermented broth. This review presents the main methods for production and separation of fumaric acid, highlighting the advantages and disadvantages of these and the potential economic impact in industry.
- Subjects :
- 0106 biological sciences
0301 basic medicine
Fumaric acid
Industrial production
Bioengineering
Context (language use)
General Medicine
Raw material
Pulp and paper industry
01 natural sciences
Applied Microbiology and Biotechnology
Environmentally friendly
03 medical and health sciences
chemistry.chemical_compound
030104 developmental biology
Petrochemical
Fumarates
chemistry
010608 biotechnology
Environmental science
Production (economics)
Fermentation
Microorganisms, Genetically-Modified
Biotechnology
Subjects
Details
- ISSN :
- 15736776 and 01415492
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Biotechnology Letters
- Accession number :
- edsair.doi.dedup.....b5f524a33099458bfa05d3a9bdaa9fbd