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A European Respiratory Society technical standard: exhaled biomarkers in lung disease
- Source :
- European Respiratory Journal, 49(4):1600965. European Respiratory Society, European Respiratory Journal, 49, 1-26, European respiratory journal, 49(4). European Respiratory Society, European Respiratory Journal, 49, 4, pp. 1-26
- Publication Year :
- 2017
-
Abstract
- Breath tests cover the fraction of nitric oxide in expired gas (FENO), volatile organic compounds (VOCs), variables in exhaled breath condensate (EBC) and other measurements. For EBC and for FENO, official recommendations for standardised procedures are more than 10 years old and there is none for exhaled VOCs and particles. The aim of this document is to provide technical standards and recommendations for sample collection and analytic approaches and to highlight future research priorities in the field. For EBC and FENO, new developments and advances in technology have been evaluated in the current document. This report is not intended to provide clinical guidance on disease diagnosis and management.Clinicians and researchers with expertise in exhaled biomarkers were invited to participate. Published studies regarding methodology of breath tests were selected, discussed and evaluated in a consensus-based manner by the Task Force members.Recommendations for standardisation of sampling, analysing and reporting of data and suggestions for research to cover gaps in the evidence have been created and summarised.Application of breath biomarker measurement in a standardised manner will provide comparable results, thereby facilitating the potential use of these biomarkers in clinical practice.
- Subjects :
- Lung Diseases
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Pathology
Settore BIO/14 - FARMACOLOGIA
BREATH CONDENSATE PH
SLEEP-APNEA SYNDROME
Technical standard
VOLATILE ORGANIC-COMPOUNDS
Nitric Oxide
01 natural sciences
NASAL NITRIC-OXIDE
OBSTRUCTIVE PULMONARY-DISEASE
EXTENDED NO ANALYSIS
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Exhaled breath condensate
Sampling (medicine)
Intensive care medicine
MASS-SPECTROMETRIC ANALYSIS
Societies, Medical
Volatile Organic Compounds
Task force
business.industry
010401 analytical chemistry
Expired gas
ELECTRONIC NOSE
MAGNETIC-RESONANCE-SPECTROSCOPY
PRIMARY CILIARY DYSKINESIA
0104 chemical sciences
Europe
Breath Tests
N/A
030228 respiratory system
Exhalation
Lung disease
Biomarker (medicine)
Molecular and Laser Physics
Sample collection
business
Biomarkers
Subjects
Details
- Language :
- English
- ISSN :
- 09031936
- Database :
- OpenAIRE
- Journal :
- European Respiratory Journal, 49(4):1600965. European Respiratory Society, European Respiratory Journal, 49, 1-26, European respiratory journal, 49(4). European Respiratory Society, European Respiratory Journal, 49, 4, pp. 1-26
- Accession number :
- edsair.doi.dedup.....b5caa8b5e618c4a4fb895765d6f717cd