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Video 5 from In Vivo Fluorescence Imaging of the Activity of CEA TCB, a Novel T-Cell Bispecific Antibody, Reveals Highly Specific Tumor Targeting and Fast Induction of T-Cell–Mediated Tumor Killing

Authors :
Marina Bacac
Christian Gerdes
Pablo Umana
Christian Klein
Markus Rudin
Szymon Stoma
Jörg Zielonka
Anne Freimoser-Grundschober
Teilo Schaller
Linda Fahrni
Tanja Fauti
Sara Colombetti
Johannes Sam
Hans-Peter Grimm
Ramanil Perera
Steffi Lehmann
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

2P time-lapse acquisition of LS174T / human PBMC cografts on day 4 after implantation (baseline), 24 h after control and 24 h after CEA TCB treatment. LS174T RFP tumor cells (red), CFSE labeled T-cells (green). Scale bar indicates 50 μm.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....b5b5873f3a8b5eb1ba7e0244642de216