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Vitamin B6 Biosynthesis: Charting the Mechanistic Landscape
- Source :
- ChemBioChem, Vol. 11, No 9 (2010) pp. 1185-1193, Chembiochem : a European journal of chemical biology
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- Enzyme of the rings: Vitamin B6 biosynthesis through the DXP independent route is catalyzed by PLP synthase. The enzyme utilizes ribose 5 phosphate glyceraldehyde 3 phosphate and ammonia to synthesize the cofactor form of the vitamin pyridoxal 5' phosphate (PLP). This review provides the emerging mechanistic details of this remarkable Pdx1:Pdx2 glutamine amidotransferase complex.
- Subjects :
- Protein Structure
Molecular Sequence Data
Biochemistry
Bacterial Proteins/chemistry/metabolism
03 medical and health sciences
chemistry.chemical_compound
Bacterial Proteins
Biosynthesis
Amino Acid Sequence
Molecular Biology
030304 developmental biology
0303 health sciences
Vitamin B 6/biosynthesis
030302 biochemistry & molecular biology
Organic Chemistry
Vitamin B 6
Protein Structure, Tertiary
ddc:580
chemistry
Pyridoxal Phosphate
Pyridoxal Phosphate/metabolism
Molecular Medicine
Vitamin b6
Sequence Alignment
Tertiary
Subjects
Details
- ISSN :
- 14397633 and 14394227
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- ChemBioChem
- Accession number :
- edsair.doi.dedup.....b5add400b09c881f7fe41ac54a069ee7
- Full Text :
- https://doi.org/10.1002/cbic.201000084