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Work disability and its determinants in patients with pituitary tumor-related disease

Authors :
Wilco C. Peul
Amir H Zamanipoor Najafabadi
Thea P. M. Vliet Vlieland
Cornelie D. Andela
Alberto M. Pereira
Anath N. V. Steffens
Nienke R. Biermasz
Wilbert B. van den Hout
Daniel J. Lobatto
Wouter R van Furth
Source :
Pituitary, 21(6), 593-604, Pituitary
Publication Year :
2018

Abstract

Introduction Pituitary tumors may have a considerable impact on patients’ functional status, including paid employment, yet research in this area is sparse. Objective To describe work disability and its determinants in patients treated for a pituitary tumor. Methods Cross-sectional study including patients treated for a pituitary tumor in the working age (18–65 years), who completed five validated questionnaires assessing work disability [Short Form-Health and Labour Questionnaire, Work Role Functioning Questionnaire 2.0 (WRFQ)], health-related quality of life (HRQoL) and utility (Short Form-36, EuroQoL) and disease burden (Leiden Bother and Needs Questionnaire-Pituitary). Additional data were extracted from the medical records (age, gender, tumor type, treatment, date of diagnosis) and self-reports (marital status, education, endocrine status). Associations of disease-specific and sociodemographic characteristics, HRQoL, and disease burden with (not) having a paid job were examined through multivariate logistic regression. Results We included 241 patients (61% female, median age 53 years, median time since diagnosis 11 years), of whom 68 (28%) were without a paid job. Patients who had acromegaly, Cushing’s disease, (pan)hypopituitarism, radiotherapy, were single, less educated, lower HRQoL, and increased disease burden were more often without a paid job (p

Details

Language :
English
Database :
OpenAIRE
Journal :
Pituitary, 21(6), 593-604, Pituitary
Accession number :
edsair.doi.dedup.....b57dd654b6aae02e3c99fb9d633df949