Generalized low‐rank nonrigid motion‐corrected reconstruction for MR fingerprinting

PURPOSE Develop a novel low-rank motion-corrected (LRMC) reconstruction for nonrigid motion-corrected MR fingerprinting (MRF). METHODS Generalized motion-corrected (MC) reconstructions have been developed for steady-state imaging. Here we extend this framework to enable nonrigid MC for transient imaging applications with varying contrast, such as MRF. This is achieved by integrating low-rank dictionary-based compression into the generalized MC model to reconstruct MC singular images, reducing motion artifacts in the resulting parametric maps. The proposed LRMC reconstruction was applied for cardiac motion correction in 2D myocardial MRF (T1 and T2 ) with extended cardiac acquisition window (~450 ms) and for respiratory MC in free-breathing 3D myocardial and 3D liver MRF. Experiments were performed in phantom and 22 healthy subjects. The proposed approach was compared with reference spin echo (phantom) and with 2D electrocardiogram-triggered/breath-hold MOLLI and T2 gradient-and-spin echo conventional maps (in vivo 2D and 3D myocardial MRF). RESULTS Phantom results were in general agreement with reference spin-echo measurements, presenting relative errors of approximately 5.4% and 5.5% for T1 and short T2 (