Preparation and characterization of organo-functionalized silicas for bilirubin removal

Hybrid-silica materials containing octyl, phenyl and urea-propyl functional groups were reported. These functionalized silicas were prepared by a via one-pot synthesis method through co-condensation of tetraethyl ortosilicate with organosilanes co-precursors. The obtained materials were analyzed by a number of techniques including scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction pattern and nitrogen sorption measurement. The main elements: morphology and surface properties of the final products that are basically dependent on the type and the quantity of functional-containing groups were fully discussed. The adsorption properties of the modified silicas were investigated against bilirubin in aqueous solution at pH 7.4, the effect of time was studied as well. The modified silicas showed a greatly increasing of adsorption capacity for bilirubin compared to pure amorphous silica. The results indicate that the type of functional-containing groups and surface properties affect the adsorption behavior. These materials show a potential application as effective adsorbents for bilirubin removal.