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Treating osteoarticular infections in a Role 2 in Chad: a bacterial epidemiological study
- Source :
- BMJ Military Health. 169:166-169
- Publication Year :
- 2021
- Publisher :
- BMJ, 2021.
-
Abstract
- IntroductionThe treatment of osteoarticular infections in Africa is a medical and surgical challenge due to the difficulties in managing antibiotic therapy after the surgical procedure. The objectives of this study were to identify the types of bacteria in osteoarticular lesions in patients treated in Chad and to determine the spectrum of resistance encountered and the efficacy of available antibiotics.Material and methodsThis is a retrospective study of all intraoperative osteoarticular and soft tissue samples taken in a French Role 2 Medical Treatment Facility of N'Djamena during surgery for chronic osteoarticular infections, in Chad, for 1 year.ResultsA total of 160 bacterial strains were identified, with a predominance of Gram-negative bacillus (GNB) and staphylococcus infections. Among staphylococci, 80% were methicillin-sensitive streptococci which were generally multidrug-sensitive. Enterococci were resistant to third-generation cephalosporins, first-generation fluoroquinolones and gentamycin. Among GNB, there was a predominance of enterobacteria compared with non-fermenting GNB, of which 52% were multidrug-resistant and produced extended spectrum beta-lactamases (ESBL).ConclusionStaphylococcus aureusinfections are most often sensitive to available antibiotics and therefore have better prognoses than infections caused by other bacteria. In contrast, in half of the cases of GNB, infections were caused by bacteria producing ESBL, thus posing the problem of multidrug-resistance, the risks of which are increased in precarious situations. Therefore, the type of bacteria appears to be a major prognostic factor in the treatment of osteoarticular infections in a Role 2 in Chad. This criterion will need to be considered before any treatment decisions are made.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
biology
Medical treatment
medicine.drug_class
business.industry
030106 microbiology
Antibiotics
Cephalosporin
Retrospective cohort study
General Medicine
medicine.disease_cause
biology.organism_classification
03 medical and health sciences
0302 clinical medicine
Internal medicine
Epidemiology
medicine
In patient
030212 general & internal medicine
business
Staphylococcus
Bacteria
Subjects
Details
- ISSN :
- 26333775 and 26333767
- Volume :
- 169
- Database :
- OpenAIRE
- Journal :
- BMJ Military Health
- Accession number :
- edsair.doi.dedup.....b4f1e39626f4a4ad82190adefcde7877