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Efficacy and safety of an acute pain service among 10,760 postoperative patients

Authors :
Giovanni Landoni
Gabriele Finco
Mario Musu
Laura Corno
Renato Meani
Francesco Deni
Alessandra Mello
Nicola Pasculli
Valeria Perotti
Laura Comotti
Luigi Beretta
Stefano Turi
Eleonora Colnaghi
Alberto Zangrillo
Deni, F.
Finco, G.
Corno, L.
Landoni, G.
Turi, S.
Colnaghi, E.
Comotti, L.
Musu, M.
Meani, R.
Mello, A.
Perotti, V.
Pasculli, N.
Beretta, L.
Zangrillo, A.
Publication Year :
2016
Publisher :
Pharmamed Mado Ltd., 2016.

Abstract

Introduction. Post-operative pain con-trol improves surgical outcome and many hospitals created multidisciplinary teams, called “Acute Pain Services” (APS). We col-lected APS data on 10,760 adult patients over a five year period, including compli-cations, side effects and patient satisfac-tion.Methods. Data on patients managed by APS in a high surgical-volume university hospital over a 5-year period were col-lected and analyzed. Data included demo-graphic characteristics, primary analgesic modality, adjuvant analgesic treatment, type of surgical procedure, Visual Ana-logue Scale, and analgesia-related side-effects and complications.Results. Patient controlled analgesia with morphine was used in 4,992 surgical pa-tients while epidural analgesia was used in 3,687 surgical patients and 1,670 pregnant women for delivery analgesia. A total of 411 patients received other forms of analgesia. No epidural haematoma was observed. A single case of respiratory depression oc-curred in an elderly patient using the pa-tient controlled analgesia system. Acetami-nophen was the most frequently adjuvant drug prescribed. Postoperative nausea and vomiting was the most frequent analgesia-related side effect. Visual Analogue Scale at rest and on movement was low on day one (0.84±1.15 and 2.05±1.67) and decreased thereafter with epidural analgesia associ-ated with better pain control following hip and liver surgery, and with less postop-erative nausea and vomiting (5.0%) when compared to morphine patient controlled analgesia (7.2%).Conclusions. An APS, with daily postop-erative visits, permits adequate post-oper-ative pain control without serious adverse events. Epidural analgesia was associated with less postoperative nausea and vom-iting and had at least similar pain control than morphine patient controlled analge-sia.

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....b4b77fc9f080b206639f96363dc4408b