Back to Search Start Over

Enhanced delivery of theranostic liposomes through NO-mediated tumor microenvironment remodeling

Authors :
Tao Tang
Biao Huang
Feng Liu
Ran Cui
Mingxi Zhang
Taolei Sun
Source :
Nanoscale. 14:7473-7479
Publication Year :
2022
Publisher :
Royal Society of Chemistry (RSC), 2022.

Abstract

Highly efficient delivery of nanoagents to the tumor region remains the primary challenge for cancer nanomedicine. Herein, we propose a NO-mediated tumor microenvironment (TME) remodeling strategy for the high-efficient delivery of nanoagents into tumor. Quantum dots (QDs) with bright fluorescence in the near-infrared IIb (NIR-IIb, 1500-1700 nm) window and high photothermal conversion efficiency were encapsulated into liposomes for the imaging-guided photothermal therapy (PTT) of tumor. The fabrication of PEG and arginine-glycine-aspartate (RGD) peptide on liposomes ensured the prolonged circulation

Details

ISSN :
20403372 and 20403364
Volume :
14
Database :
OpenAIRE
Journal :
Nanoscale
Accession number :
edsair.doi.dedup.....b477738a4678fd9760d9848891b77899