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The Impact of Therapeutic Hypothermia Used to Treat Anoxic Brain Injury After Cardiopulmonary Resuscitation on Organ Donation Outcomes
- Source :
- Therapeutic hypothermia and temperature management. 9(4)
- Publication Year :
- 2019
-
Abstract
- Therapeutic hypothermia (TH) is clinically used to improve neurologic outcomes in patients with anoxic brain injury after cardiopulmonary resuscitation (CPR). For patients that regress and become organ donors after neurologic determination of death (DNDDs), the impact of TH received before determination of death on organ donation outcomes remains unknown. A prospective observational study of all adult DNDDs that received CPR and had anoxia as a cause of death from March 2013 to December 2014 was conducted across 20 organ procurement organizations (OPOs) in the United States. Main outcome measures included organs transplanted per donor (OTPD), specific organ transplantation rates, and recipient graft outcomes. One thousand ninety eight DNDDs met inclusion criteria, with 46% having received TH before determination of death. DNDDs with hypothermia before death had a similar number of OTPD (2.74 vs. 2.69
- Subjects :
- Adult
Male
medicine.medical_treatment
Delayed Graft Function
Critical Care and Intensive Care Medicine
03 medical and health sciences
0302 clinical medicine
Hypothermia, Induced
Medicine
Humans
In patient
Organ donation
Cardiopulmonary resuscitation
Prospective Studies
Hypoxia, Brain
Anoxic brain injury
business.industry
030208 emergency & critical care medicine
Hypothermia
Middle Aged
Kidney Transplantation
Cardiopulmonary Resuscitation
Tissue Donors
Anesthesiology and Pain Medicine
Anesthesia
Female
medicine.symptom
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 21537933
- Volume :
- 9
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Therapeutic hypothermia and temperature management
- Accession number :
- edsair.doi.dedup.....b45d57474b520769a708f143d99dfe13