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Outcomes in children with hemophilia A with inhibitors: Results from a noninterventional study
- Source :
- Biblos-e Archivo. Repositorio Institucional de la UAM, instname, Biblos-e Archivo: Repositorio Institucional de la UAM, Universidad Autónoma de Madrid
- Publication Year :
- 2019
-
Abstract
- Background: Data regarding management of pediatric persons with hemophilia A (PwHA) with factor VIII (FVIII) inhibitors are limited. This prospective noninterventional study (NCT02476942) evaluated annualized bleeding rates (ABRs), safety, and health-related quality of life (HRQoL) in pediatric PwHA with FVIII inhibitors. Procedure: PwHA aged<br />Was funded by F. Hoffmann-La Roche Ltd.
- Subjects :
- FVIII
Male
medicine.medical_specialty
Medicina
Antibodies, Monoclonal, Humanized
Hemophilia A
03 medical and health sciences
0302 clinical medicine
Quality of life
Internal medicine
Antibodies, Bispecific
medicine
Humans
Prospective Studies
Prospective cohort study
Adverse effect
Child
Retrospective Studies
Emicizumab
emicizumab
Factor VIII
business.industry
Standard treatment
blood coagulation factor inhibitors
noninterventional study
Infant
Retrospective cohort study
Hematology
Hemarthrosis
medicine.disease
health-related quality of life
Upper respiratory tract infection
Treatment Outcome
Oncology
030220 oncology & carcinogenesis
Child, Preschool
Pediatrics, Perinatology and Child Health
Quality of Life
hemophilia A
Female
business
030215 immunology
Follow-Up Studies
Subjects
Details
- ISSN :
- 15455017
- Volume :
- 67
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Pediatric bloodcancerREFERENCES
- Accession number :
- edsair.doi.dedup.....b4530e3089954b7a6d0ecfb3e3aaf2fd