Back to Search Start Over

Characteristics and outcomes of atrial fibrillation in patients without traditional risk factors

Authors :
Marie Ntep-Gweth
Philip Joseph
Supachai Tanosmsup
Stuart J. Connolly
Mariëlle Kloosterman
Michael D. Ezekowitz
Guy Amit
Lars Wallentin
Alex Grinvalds
Alvaro Avezum
Shun Fu Lee
Salim Yusuf
Jonas Oldgren
David Conen
Tyler W. Barrett
Ratika Parkash
Isabelle C. Van Gelder
Jorge A. Wong
William F. McIntyre
Jeff S. Healey
Cardiovascular Centre (CVC)
Source :
Europace, Europace, 22(6), 870-877. Oxford University Press
Publication Year :
2020

Abstract

Aims Data on patient characteristics, prevalence, and outcomes of atrial fibrillation (AF) patients without traditional risk factors, often labelled ‘lone AF’, are sparse. Methods and results The RE-LY AF registry included 15 400 individuals who presented to emergency departments with AF in 47 countries. This analysis focused on patients without traditional risk factors, including age ≥60 years, hypertension, coronary artery disease, heart failure, left ventricular hypertrophy, congenital heart disease, pulmonary disease, valve heart disease, hyperthyroidism, and prior cardiac surgery. Patients without traditional risk factors were compared with age- and region-matched controls with traditional risk factors (1:3 fashion). In 796 (5%) patients, no traditional risk factors were present. However, 98% (779/796) had less-established or borderline risk factors, including borderline hypertension (130–140/80–90 mmHg; 47%), chronic kidney disease (eGFR 30; 19%), diabetes (5%), excessive alcohol intake (>14 units/week; 4%), and smoking (25%). Compared with patients with traditional risk factors (n = 2388), patients without traditional risk factors were more often men (74% vs. 59%, P Conclusion Almost all patients without traditionally defined AF risk factors have less-established or borderline risk factors. These patients have a favourable 1-year prognosis, but risk of AF-related re-hospitalization remains high. Greater emphasis should be placed on recognition and management of less-established or borderline risk factors.

Details

Language :
English
ISSN :
10995129
Volume :
22
Issue :
6
Database :
OpenAIRE
Journal :
Europace
Accession number :
edsair.doi.dedup.....b4344ab6bc962b407632a87da3a62746