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Family-Centered Care Enhanced Neonatal Neurophysiological Function in Preterm Infants: Randomized Controlled Trial
- Source :
- Physical therapy. 99(12)
- Publication Year :
- 2019
-
Abstract
- Background Family-centered intervention for preterm infants has shown short- to medium-term developmental benefits; however, the neurological effects of intervention have rarely been explored. Objective The objectives of this study were to examine the effect of a family-centered intervention program (FCIP) on neurophysiological functions in preterm infants with very low birth weight (VLBW; birth weight of Design This was a multicenter, single-blind randomized controlled trial. Setting The study took place in 3 medical centers in northern and southern Taiwan. Participants Two hundred fifty-one preterm infants with VLBW were included. Intervention The FCIP group received a family-centered intervention and the UCP group received standard care during hospitalization. Measurements Infants were assessed in terms of neurobehavioral performance using the Neonatal Neurobehavioral Examination–Chinese version, and their neurophysiological function was assessed using electroencephalography/event-related potentials during sleep and during an auditory oddball task during the neonatal period. Results The FCIP promoted more mature neurophysiological function than the UCP, including greater negative mean amplitudes of mismatch negativities in the left frontal region in the oddball task in all infants, lower intrahemispheric prefrontal-central coherence during sleep in infants who were small for gestational age, and higher interhemispheric frontal coherence during sleep in those who were appropriate for gestational age. Furthermore, interhemispheric coherence was positively associated with the total neurobehavioral score in preterm infants who were appropriate for gestational age (r = 0.20). Limitations The fact that more parental adherence strategies were used in the FCIP group than in the UCP group might have favored the intervention effect in this study. Conclusions Family-centered intervention facilitates short-term neurophysiological maturation in preterm infants with VLBW in Taiwan.
- Subjects :
- Pediatrics
medicine.medical_specialty
Birth weight
Taiwan
Physical Therapy, Sports Therapy and Rehabilitation
Electroencephalography
Motor Activity
Family centered care
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
030225 pediatrics
Intervention (counseling)
Early Medical Intervention
Patient-Centered Care
Reflex
medicine
Humans
Infant, Very Low Birth Weight
Family
Single-Blind Method
Oddball paradigm
Evoked Potentials
Observer Variation
medicine.diagnostic_test
business.industry
Infant, Newborn
medicine.disease
Neurophysiological Monitoring
Low birth weight
Infant Behavior
Small for gestational age
medicine.symptom
business
Sleep
030217 neurology & neurosurgery
Infant, Premature
Subjects
Details
- ISSN :
- 15386724
- Volume :
- 99
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Physical therapy
- Accession number :
- edsair.doi.dedup.....b41f362e81b3e61ce2dca2e45958b462