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Wegener's granulomatosis presenting as multiple bilateral renal masses
- Source :
- Nephrology Dialysis Transplantation. 19:984-987
- Publication Year :
- 2004
- Publisher :
- Oxford University Press (OUP), 2004.
-
Abstract
- Wegener’s granulomatosis (WG) is a systemic disease characterized pathologically by necrotizing granulomatous inflammation of the respiratory tract and generalized vasculitis involving mediumand smallsized vessels. Kidney involvement is usually manifested as a focal segmental necrotizing glomerulonephritis, with crescents [1]. Anti-neutrophil cytoplasm antibody (ANCA) testing has provided a very useful diagnostic aid. The majority of patients with WG have antibodies towards proteinase 3 (PR3-ANCA) (>70%), but antibodies towards myeloperoxidase (MPO-ANCA) is seen in 20% of cases. A few patients (
- Subjects :
- Male
Systemic disease
Pathology
medicine.medical_specialty
medicine.medical_treatment
urologic and male genital diseases
Proteinase 3
medicine
Humans
cardiovascular diseases
Aged
Transplantation
Kidney
biology
business.industry
Vascular disease
Granulomatosis with Polyangiitis
medicine.disease
medicine.anatomical_structure
Nephrology
Myeloperoxidase
biology.protein
Kidney Diseases
Hemodialysis
Vasculitis
business
Kidney disease
Subjects
Details
- ISSN :
- 14602385 and 09310509
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Nephrology Dialysis Transplantation
- Accession number :
- edsair.doi.dedup.....b41a8cf7c1d8dadf01a0156bc6e99fe8
- Full Text :
- https://doi.org/10.1093/ndt/gfh058