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Wegener's granulomatosis presenting as multiple bilateral renal masses

Authors :
Nelson Leung
Donna J. Lager
Michael L. Blute
Fernando C. Fervenza
Steven R. Ytterberg
Ulrich Specks
Source :
Nephrology Dialysis Transplantation. 19:984-987
Publication Year :
2004
Publisher :
Oxford University Press (OUP), 2004.

Abstract

Wegener’s granulomatosis (WG) is a systemic disease characterized pathologically by necrotizing granulomatous inflammation of the respiratory tract and generalized vasculitis involving mediumand smallsized vessels. Kidney involvement is usually manifested as a focal segmental necrotizing glomerulonephritis, with crescents [1]. Anti-neutrophil cytoplasm antibody (ANCA) testing has provided a very useful diagnostic aid. The majority of patients with WG have antibodies towards proteinase 3 (PR3-ANCA) (>70%), but antibodies towards myeloperoxidase (MPO-ANCA) is seen in 20% of cases. A few patients (

Details

ISSN :
14602385 and 09310509
Volume :
19
Database :
OpenAIRE
Journal :
Nephrology Dialysis Transplantation
Accession number :
edsair.doi.dedup.....b41a8cf7c1d8dadf01a0156bc6e99fe8
Full Text :
https://doi.org/10.1093/ndt/gfh058