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Gut microbial flora, prebiotics, and probiotics in IBD: their current usage and utility
- Source :
- BioMed Research International, Vol 2013 (2013), BioMed Research International
- Publication Year :
- 2013
-
Abstract
- Inflammatory bowel diseases are chronic diseases affecting the gastrointestinal tract, whose major forms are represented by Crohn’s disease (CD) and ulcerative colitis (UC). Their etiology is still unclear, although several factors have been identified as major determinants for induction or relapses. Among these, the role of the “forgotten organ”, gut microbiota, has become more appreciated in recent years. The delicate symbiotic relationship between the gut microbiota and the host appears to be lost in IBD. In this perspective, several studies have been conducted to assess the role of prebiotics and probiotics in gut microbiota modulation. This is a minireview aimed to address in an easy format (simple questions-simple answers) some common issues about the theme. An update on the role of selected constituents of gut microbiota in the pathogenesis of IBD is presented together with the analysis of the efficacy of gut microbiota modulation by prebiotics and probiotics administration in the management of IBD.
- Subjects :
- Settore MED/12 - GASTROENTEROLOGIA
lcsh:Medicine
Review Article
Disease
INLAMMATORY
Gut flora
Inflammatory bowel diseases
Inflammatory bowel disease
digestive system
General Biochemistry, Genetics and Molecular Biology
inflammatory bowel disease
Flora (microbiology)
medicine
Humans
ulcerative colitis
Crohn's disease
Gastrointestinal tract
General Immunology and Microbiology
biology
Microbiota
lcsh:R
Settore MED/09 - MEDICINA INTERNA
Inflammatory Bowel Diseases
Crohn disease
Gut microbial flora
General Medicine
medicine.disease
biology.organism_classification
Ulcerative colitis
digestive system diseases
Intestines
probiotics
Immunology
Microbial Interactions
Gut microbial flora, prebiotics,probiotics, Inflammatory bowel diseases, Crohn disease, ulcerative colitis
prebiotics
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- BioMed Research International, Vol 2013 (2013), BioMed Research International
- Accession number :
- edsair.doi.dedup.....b41778d0af998d22206f18bf5088128e