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Dose-response analysis of infants prenatally exposed to methyl mercury: An application of a single compartment model to single-strand hair analysis
- Source :
- Environmental Research. 49:318-332
- Publication Year :
- 1989
- Publisher :
- Elsevier BV, 1989.
-
Abstract
- A new method of estimating fetal exposure is used in a dose-response analysis of data from the 1971 outbreak of methyl mercury poisoning in rural Iraq. An X-ray fluorescence instrument for the measurement of single strands of human hair was employed to obtain longitudinal profiles recapitulating fetal exposure. Logit and hockey-stick models as well as nonparametric smoothing are used to describe data on delayed development and central nervous system abnormality.
- Subjects :
- Central Nervous System
Nervous system
Single compartment
Developmental Disabilities
Physiology
chemistry.chemical_element
Food Contamination
Fetal exposure
Biochemistry
Mercury poisoning
Toxicology
Pregnancy
Risk Factors
medicine
Humans
Maternal-Fetal Exchange
General Environmental Science
Fetus
Chemistry
Hair analysis
Infant, Newborn
Spectrometry, X-Ray Emission
Bread
Methylmercury Compounds
Models, Theoretical
medicine.disease
Mercury (element)
medicine.anatomical_structure
Iraq
Female
Hair
Single strand
Subjects
Details
- ISSN :
- 00139351
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Environmental Research
- Accession number :
- edsair.doi.dedup.....b40608197a6904aaea7b6cc45683d61b