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Scleral Thickness following Fluocinolone Acetonide Implant (Retisert)
- Source :
- Ocular Immunology and Inflammation. 18:305-313
- Publication Year :
- 2010
- Publisher :
- Informa UK Limited, 2010.
-
Abstract
- To evaluate whether intravitreal fluocinolone acetonide (FA) implantation (Retisert) leads to scleral thinning.Scleral thickness was measured at the pars plana region (4 quadrants) with anterior segment OCT (Visante) in FA implanted eyes (18) with noninfectious posterior uveitis in comparison to eyes with prior vitrectomy (8), and normal eyes without prior surgery (30).Mean scleral thickness in normal (nonsurgical) eyes was 0.99/0.93/0.88/0.86, and 0.92 mm in the inferonasal/inferotemporal/superotemporal/superonasal quadrants, and overall, respectively. Sclera was thinner in each quadrant of the FA implanted eyes compared to the fellow or nonsurgical eyes, although none reached statistical significance, as the differences were small. However, a few FA implanted eyes demonstrated more dramatic scleral thinning than others.FA implant appears to lead to statistically nonsignificant scleral thinning overall with few exceptions. Clinicians should be aware of potential scleral thinning in select cases, important for reimplantation and long-term follow-up.
- Subjects :
- Adult
Male
Pars plana
medicine.medical_specialty
genetic structures
medicine.medical_treatment
Visual Acuity
Vitrectomy
Quadrant (abdomen)
Fluocinolone acetonide
Recurrence
Ophthalmology
Scleral thinning
medicine
Humans
Immunology and Allergy
Glucocorticoids
Drug Implants
business.industry
Uveitis, Posterior
Middle Aged
eye diseases
Scleral Diseases
Sclera
Treatment Outcome
medicine.anatomical_structure
Fluocinolone Acetonide
Posterior uveitis
Female
sense organs
Implant
business
medicine.drug
Subjects
Details
- ISSN :
- 17445078 and 09273948
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Ocular Immunology and Inflammation
- Accession number :
- edsair.doi.dedup.....b3ce6d9ac590c5e031f6f4c6d0301415