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Diagnosis of acute tonsillopharyngitis in primary care: a new approach for low-resource settings
- Source :
- Journal of chemotherapy (Florence, Italy). 25(3)
- Publication Year :
- 2013
-
Abstract
- Background: Diagnosing GABHS (Group A-beta Hemolytic Streptococcus) tonsillopharyngitis by clinical scoring is a recommended approach in developed countries, but there is still much controversy for low resource settings.Aim: We aimed to assess the impact of Centor criteria with the support of practical laboratory tests.Methods: We prospectively included patients complaining sore throat (N = 282). We evaluated them in terms of Centor scoring and performed white blood cell count (WBC), C-reactive protein (CRP), rapid antigen detecting test, and throat culture.Results: In GABHS cases (n = 32, 11·3%), two of the criteria were observed to be positive in more than half of the cases (n = 19, 59·3%), while 13 (40·7%) cases met three/four criteria. The specificity of having two criteria was found to be 65·5% and increased to 91·5% after including CRP and WBC.Conclusion: Centor criteria could be safely used to reduce unnecessary antibiotic usage for tonsillopharyngitis in developing countries.
- Subjects :
- Sore Throat
Tonsillitis
Streptococcus
Male
Turkey
Receiver operating characteristic
Inappropriate Prescribing
Streptococcal pharyngitis
Streptococcus group A
Leukocyte Count
Validation
Sore throat
Pathology
Medicine
Pharmacology (medical)
Young adult
Child
Tonsillopharyngitis
Aged, 80 and over
Biological markers
C reactive protein
Strep
Diagnostic test accuracy study
Pharyngitis
Hemolytic streptococcus
Middle Aged
Primary care
Management
Erythromycin
Bacterial Typing Techniques
medicine.anatomical_structure
C-Reactive Protein
Oncology
Antibiotic use
Infectious diseases
Penicillin V
Female
Acute tonsillopharyngitis
medicine.symptom
CRP
Human
Antigen detection
Adult
medicine.medical_specialty
Adolescent
Cost Control
Low resource
Rapid antigen detecting test
Streptococcus pyogenes
Predictive value
Centor scoring
Major clinical study
WBC
Guidelines
Sensitivity and Specificity
Article
Young Adult
Primary medical care
Centor criteria
Throat
Internal medicine
Streptococcal Infections
otorhinolaryngologic diseases
Adults
Humans
Prospective study
Developing Countries
Physical Examination
Aged
Pharmacology
Primary Health Care
business.industry
Pharmacology & pharmacy
Questionnaire
Amoxicillin
Surgery
stomatognathic diseases
Antigen-detection test
Preschool child
Throat culture
School child
business
Prediction
Biomarkers
Subjects
Details
- ISSN :
- 19739478
- Volume :
- 25
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of chemotherapy (Florence, Italy)
- Accession number :
- edsair.doi.dedup.....b3bbc201966ef599f895f35f77c13d29