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Impact of Preoperative Nutritional Indicator on Poor Postoperative Outcomes in Geriatric Patients with Colorectal Cancer
- Source :
- Nutrition and cancer. 74(4)
- Publication Year :
- 2021
-
Abstract
- The present study aimed to analyze the association between preoperative nutritional assessment and poor postoperative outcomes in geriatric patients with colorectal cancer. This retrospective study included 138 patients aged ≥80 years with colorectal cancer who underwent surgery from January 2013 to December 2018. Patients were classified into two groups according to outcomes, poor group and normal group. Clinicopathological factors were compared between the groups, and the relationships of several nutritional indices were examined. There was no significant difference in sex, age, or preoperative comorbidities. There were significant differences in volume of blood loss and proportion of laparoscopic surgery. The group with poor outcomes had significantly higher neutrophil/lymphocyte ratio (NLR) and modified Glasgow prognostic score (mGPS) than the group with normal outcomes. Multivariate analysis revealed that open approach, high NLR, and category D mGPS were independent risk factors of poor postoperative outcomes in elderly patients with colorectal cancer. Our findings indicate that mGPS and NLR could be useful nutritional indicators of short-term outcomes of surgical treatment in geriatric patients with colorectal cancer. They can be evaluated based on albumin and C-reactive protein levels and blood count, which are inexpensive and beneficial to use in routine clinical practice.
- Subjects :
- Laparoscopic surgery
Cancer Research
medicine.medical_specialty
Multivariate analysis
Colorectal cancer
Neutrophils
medicine.medical_treatment
Medicine (miscellaneous)
Prognostic score
Blood loss
Internal medicine
Medicine
Humans
Lymphocytes
Aged
Retrospective Studies
Nutrition and Dietetics
business.industry
Significant difference
Retrospective cohort study
medicine.disease
Prognosis
Normal group
Nutrition Assessment
Oncology
business
Colorectal Neoplasms
Subjects
Details
- ISSN :
- 15327914
- Volume :
- 74
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Nutrition and cancer
- Accession number :
- edsair.doi.dedup.....b3b6111a8771f26597b5c2bb274ff4c3