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Impaired Fetal Growth and Low Plasma Volume in Adult Life
- Source :
- Obstetrics and Gynecology, 118, 6, pp. 1314-22, Obstetrics and Gynecology, 118, 1314-22, Obstetrics and Gynecology, 118(6), 1314-1322. LIPPINCOTT WILLIAMS & WILKINS
- Publication Year :
- 2011
-
Abstract
- Contains fulltext : 97020.pdf (Publisher’s version ) (Closed access) OBJECTIVE: : To estimate whether normotensive women who were born small for gestational age have low plasma volume in adult life, which is associated with later chronic hypertension. METHODS: : In 280 normotensive women with a history of hypertension in pregnancy, we recorded recalled gestational age and weight at birth and measured plasma volume (I-human serum albumin indicator dilution method). To correct for possible confounders, we recorded recent obstetric history and measured in each individual all constituents of the metabolic syndrome (World Health Organization criteria), sex hormones (progesterone and estradiol), renal function, and cardiac performance at rest (echocardiography). We estimated daily activity level with a validated questionnaire (Short Questionnaire to Assess Health-enhancing physical activity). We studied the relation between women's own birth weight centile and her adult plasma volume (mL) and adjusted for the effects of confounding variables using multiple linear regression analysis. RESULTS: : Birth weight correlated positively with adult plasma volume (P
- Subjects :
- Adult
medicine.medical_specialty
Birth weight
Hypertension in Pregnancy
Physiology
Renal function
Cardiovascular diseases Hormonal regulation [NCEBP 14]
Internal medicine
Medicine
Birth Weight
Humans
Plasma Volume
Retrospective Studies
Body surface area
Fetal Growth Retardation
Cardiovascular diseases [NCEBP 14]
business.industry
Confounding
Infant, Newborn
Obstetrics and Gynecology
Gestational age
Functional imaging [IGMD 1]
medicine.disease
Confidence interval
Endocrinology
Hypertension
Infant, Small for Gestational Age
Linear Models
Small for gestational age
Female
Cardiovascular diseases Health aging / healthy living [NCEBP 14]
business
Subjects
Details
- Language :
- English
- ISSN :
- 00297844
- Volume :
- 118
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Obstetrics and Gynecology
- Accession number :
- edsair.doi.dedup.....b3a3d17e3268d7faaf5f8ec4b11159d1