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Efficient Self-Assembled MicroRNA Delivery System Consisting of Cholesterol-Conjugated MicroRNA and PEGylated Polycationic Polymer for Tumor Treatment

Authors :
Seungjoo Haam
Seungmin Han
Byeonggeol Mun
Hye Young Son
Eunji Jang
Yuna Choi
Yong Min Huh
Source :
ACS Applied Bio Materials. 2:2219-2228
Publication Year :
2019
Publisher :
American Chemical Society (ACS), 2019.

Abstract

MicroRNA (miR), a key molecule involved in endogenous RNA interference, is a promising therapeutic agent. In vivo delivery of miR, however, is a major factor limiting its application because its po...

Details

ISSN :
25766422
Volume :
2
Database :
OpenAIRE
Journal :
ACS Applied Bio Materials
Accession number :
edsair.doi.dedup.....b39230fa1caaf317cf83ba3e3a1b4c4f