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Relationship between perfusion index and patent ductus arteriosus in preterm infants
- Source :
- Pediatric Research. 81:775-779
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- Perfusion index (PI) is a noninvasive measure of perfusion. ΔPI (difference between pre- and postductal PI) may identify hemodynamically significant PDA. However, studies are limited to brief and intermittent ΔPI sampling. Our objective is to assess the value of continuous high resolution ΔPI monitoring in the diagnosis of PDA. Continuous ΔPI monitoring in preterm infants was prospectively performed using two high-resolution pulse oximeters. Perfusion Index measures (ΔPI mean and variability, pre- and postductal PI) were analyzed over a 4-h period prior to echocardiography. A cardiologist blinded to the results evaluated for PDA on echocardiography. Linear mixed regression models were utilized for analyses. We obtained 31 echocardiography observations. Mean ΔPI (−0.23 vs. 0.16; P < 0.05), mean pre-PI (0.86 vs. 1.26; P < 0.05), and ΔPI variability (0.39 vs. 0.61; P = 0.05) were lower in infants with PDA compared to infants without PDA at the time of echocardiography. Mean ΔPI, ΔPI variability, and mean pre-PI measured 4 h prior to echocardiography detect PDA in preterm infants. PI is dynamic and should be assessed continuously. Perfusion index is a promising bedside measurement to identify PDA in preterm infants.
- Subjects :
- Male
medicine.medical_specialty
Time Factors
Perfusion index
education
Mixed regression
High resolution
Gestational Age
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Coronary Circulation
030225 pediatrics
Ductus arteriosus
Internal medicine
medicine
Humans
Oximetry
Prospective Studies
030212 general & internal medicine
Ductus Arteriosus, Patent
business.industry
Pediatric research
Infant, Newborn
Echocardiography, Doppler, Color
Oxygen
medicine.anatomical_structure
Point-of-Care Testing
Infant, Extremely Premature
Pulsatile Flow
Pediatrics, Perinatology and Child Health
Linear Models
Cardiology
Female
business
Perfusion
Biomarkers
Pulse oximeters
Subjects
Details
- ISSN :
- 15300447 and 00313998
- Volume :
- 81
- Database :
- OpenAIRE
- Journal :
- Pediatric Research
- Accession number :
- edsair.doi.dedup.....b333220b5e0bf2af718530cf697aa598