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Two new daphnane diterpenes from the roots of Stelleropsis tianschanica
- Source :
- Journal of Asian Natural Products Research. 20:1116-1122
- Publication Year :
- 2017
- Publisher :
- Informa UK Limited, 2017.
-
Abstract
- Two new daphnane diterpenes named tianchaterpenes A and B were isolated from the roots of Stelleropsis tianschanica. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HRESIMS. Compounds 1 and 2 were evaluated for their cytotoxic activities against HeLa and HCT-8 cell lines. The results showed that all compounds displayed weak cytotoxicities to the HeLa cells and were inactive to the HCT-8 cells.
- Subjects :
- Models, Molecular
Pharmacology
Magnetic Resonance Spectroscopy
Molecular Structure
010405 organic chemistry
Chemistry
Stereochemistry
Organic Chemistry
Pharmaceutical Science
General Medicine
Antineoplastic Agents, Phytogenic
Plant Roots
01 natural sciences
0104 chemical sciences
Analytical Chemistry
010404 medicinal & biomolecular chemistry
Complementary and alternative medicine
Cell Line, Tumor
Drug Discovery
Humans
Molecular Medicine
Spectral analysis
Diterpenes
Drug Screening Assays, Antitumor
Drugs, Chinese Herbal
Subjects
Details
- ISSN :
- 14772213 and 10286020
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Journal of Asian Natural Products Research
- Accession number :
- edsair.doi.dedup.....b2f20fb8ef2426e0c5af871560bd6f0d