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Kalshiolin A, new lignan from Kalimeris shimadai
- Publication Year :
- 2019
- Publisher :
- Taylor & Francis, 2019.
-
Abstract
- The Asian plant Kalimeris shimadai has been used as food and ethnologic medicine for over a thousand years. In this study, we isolated and identified one new lignan, kalshiolin A (1), and 12 known lignans (2–13). The structures were characterized by the comprehensive analyses of spectroscopic data (HR-ESI-MS, IR, 1D, and 2D-NMR) and the absolute configuration of 1 was determined from ECD calculations. The new compound 1 was also screened for cytotoxic activity but did not show significant potency (IC50 35.9–43.3 μM) against A549, MDA-MB-231, MCF7, KB, and KB-VIN cell lines.
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....b2f17bba911a56427e80a984aeee3b3f
- Full Text :
- https://doi.org/10.6084/m9.figshare.8268446