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Exclusive breastfeeding, maternal HIV disease, and the risk of clinical breast pathology in HIV-infected, breastfeeding women
- Source :
- American Journal of Obstetrics and Gynecology. 205:344.e1-344.e8
- Publication Year :
- 2011
- Publisher :
- Elsevier BV, 2011.
-
Abstract
- Objective The objective of the study was to examine the relationship between breastfeeding patterns, markers of maternal human immunodeficiency virus (HIV) disease, and woman's breast pathology. Study Design Secondary data analysis from a randomized breastfeeding trial including 947 HIV-infected women (n = 5982 visits) from breastfeeding initiation until 6 months postpartum; 1 month after breastfeeding cessation; or loss to follow-up or death. Generalized estimating equations assessed the effects of breastfeeding pattern and maternal HIV status on breast pathology. Results One hundred ninety women (20.1%) had a breast problem; 86 (9.1%) had mastitis; and 31 (3.3%) had abscess. After confounder adjustment, nonexclusively breastfeeding women had an increased risk of breast problems (odds ratio, 1.98; 95% confidence interval, 1.33–2.95) and mastitis (odds ratio, 2.87, 95% confidence interval, 1.69–4.88) compared with exclusive breastfeeders. Women with a CD4 count less than 200 cells/μL tended to have an increased risk of abscess. Conclusion Nonexclusive breastfeeding significantly increased the risk of breast pathology. Exclusive breastfeeding is not only optimal for infant health but it also benefits mothers by reducing breast problems.
- Subjects :
- Adult
medicine.medical_specialty
Breastfeeding
HIV Infections
Disease
Article
law.invention
Breast Diseases
Randomized controlled trial
Risk Factors
law
medicine
Humans
Prospective Studies
Prospective cohort study
business.industry
Obstetrics
Obstetrics and Gynecology
Odds ratio
medicine.disease
Confidence interval
Mastitis
Breast Feeding
Female
business
Breast feeding
Subjects
Details
- ISSN :
- 00029378
- Volume :
- 205
- Database :
- OpenAIRE
- Journal :
- American Journal of Obstetrics and Gynecology
- Accession number :
- edsair.doi.dedup.....b2d3adec1cb9edd2fb9e7816c3e8d702