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Origin of Enantioselectivity in the Jacobsen Epoxidation of Olefins

Authors :
László Kürti
E. J. Corey
Megan M. Blewett
Source :
Organic Letters. 11:4592-4595
Publication Year :
2009
Publisher :
American Chemical Society (ACS), 2009.

Abstract

It is proposed that facial selectivity in the Jacobsen epoxidation is determined by electrostatic and steric factors with a two-step pathway involving a carbocationic intermediate.

Details

ISSN :
15237052 and 15237060
Volume :
11
Database :
OpenAIRE
Journal :
Organic Letters
Accession number :
edsair.doi.dedup.....b274fbc30cc8ba25b4021619163cc48f
Full Text :
https://doi.org/10.1021/ol901859d