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The rate of resolution of clot burden measured by pulmonary CT angiography in patients with acute pulmonary embolism
- Source :
- AJR. American journal of roentgenology. 200(4)
- Publication Year :
- 2013
-
Abstract
- The purpose of this article is to quantitatively assess the rate of resolution of clot burden detected on pulmonary CT angiography (CTA) in patients with acute pulmonary embolism (PE).We evaluated 111 consecutive patients (55 men and 56 women) in a retrospective cohort who were diagnosed with PE by pulmonary CTA and had at least one follow-up pulmonary CTA within 1 year. Two radiologists in consensus measured the volume of each clot using a semiautomated quantification program. Semiquantitative measures of clot burden were also computed. The resolution rates of the total clot volume, as well as clot volumes of the central (main and lobar) and peripheral vessels (segmental and subsegmental), were analyzed.The mean (± SD) clot volume per study was 3403.3 ± 6505.6 mm(3) at baseline and 531.6 ± 2383.5 mm(3) at the follow-up pulmonary CTA. Overall, 85 patients (77% ) showed complete resolution at the follow-up pulmonary CTA. Complete resolution was seen in 17 of 30 patients (56.7%) at a follow-up interval of 1-14 days, in 24 of 31 patients (77.4%) at 29-90 days, and in 32 of 34 patients (94.1%) after 90 days. The total clot volume measurements summed for all patients decreased by 78% (central clot, 69.4%; peripheral clot, 86.0%) at 14 days, by 96.6% (central clot, 93.4%; peripheral clot, 100%) at 90 days, and by 97.7% (central clot, 95.9%; peripheral clot, 100%) after 90 days.Clot burden resolved completely in 77% of patients during the follow-up period. Our analysis showed that clots resolved faster in the peripheral arteries than in the central pulmonary arteries.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Pulmonary Artery
Article
X ray computed
medicine.artery
medicine
Humans
Radiology, Nuclear Medicine and imaging
Peripheral vessels
In patient
Aged
Retrospective Studies
Aged, 80 and over
medicine.diagnostic_test
business.industry
Angiography
Retrospective cohort study
General Medicine
Middle Aged
medicine.disease
Complete resolution
Pulmonary embolism
Pulmonary artery
Disease Progression
Female
Radiology
business
Pulmonary Embolism
Tomography, X-Ray Computed
Subjects
Details
- ISSN :
- 15463141
- Volume :
- 200
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- AJR. American journal of roentgenology
- Accession number :
- edsair.doi.dedup.....b26f74568d117ffcb3748f1cf3af696f