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Mechanisms of action of microdeformational wound therapy
- Source :
- Seminars in Cell & Developmental Biology. 23:987-992
- Publication Year :
- 2012
- Publisher :
- Elsevier BV, 2012.
-
Abstract
- Microdeformational Wound Therapy (MDWT) is a class of medical devices that have revolutionized the treatment of complex wounds over the last 20 years. These devices, are a subset of Negative Pressure Wound Therapy (NPWT), in which there is a highly porous interface material placed between the wound and a semi-occlussive dressing and connected to suction. The porous interface material acts to deform the wound on a micro scale promoting cellular proliferation. These devices appear to significantly improve the speed of healing in many wounds, facilitate granulation tissue formation and reduce the complexity of subsequent reconstructive operations. The mechanisms through which such effects are obtained are beginning to be better understood through basic research and clinical trials. Further work in this field is likely to yield devices that are designed to treat specific wound types.
- Subjects :
- Suction (medicine)
Wound therapy
medicine.medical_treatment
Wounds, Penetrating
Occlusive Dressings
Suction
Biology
Cicatrix
Basic research
Negative-pressure wound therapy
Highly porous
medicine
Animals
Humans
Regeneration
Cell Proliferation
Skin
Clinical Trials as Topic
Wound Healing
integumentary system
Granulation tissue
Cell Biology
Occlusive dressing
medicine.anatomical_structure
Granulation Tissue
Wound healing
Negative-Pressure Wound Therapy
Developmental Biology
Biomedical engineering
Subjects
Details
- ISSN :
- 10849521
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Seminars in Cell & Developmental Biology
- Accession number :
- edsair.doi.dedup.....b2589f3e0bd6fda86a0d8a806d2f6aaf