Immunologic tolerance to skin allograft after graft-versus-host disease

We report the observation of a young girl suffering from acute myeloid luekemia who developed chronic graft-versus-host disease with major skin involvement after a bone marrow graft from her histocompatible brother. She developed an immunologic tolerance to her brother's skin, which was used to correct the severe joint contractures, sequelae of the graft-versus-host disease.