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Some Phenomena Associated with the Development of Trypanosoma Brucei Rhodesiense Infections in the Tsetse Fly, Glossina Morsitans *
- Source :
- The American Journal of Tropical Medicine and Hygiene. 30:570-574
- Publication Year :
- 1981
- Publisher :
- American Society of Tropical Medicine and Hygiene, 1981.
-
Abstract
- Immature salivary gland (SG) infections averaging 10(3) parasites per fly can apparently develop into mature gland infections averaging 10(5) parasites per fly in as little as 4 days. Frequently flies which extrude parasites in their saliva prove to have no parasites in the SG, but often show trypanosomes in the esophagus, cibarial pump, and proboscis. In some instances, SG infections have cleared, resulting in a loss of infectivity. Results of studying numbers of parasites regurgitated upon feeding or probing have shown that number to be highly variable and not necessarily related either to previous feeding status or the total number of parasites in the glands. Cloning of metacyclics in mice has been achieved, indicating that the minimum effective dose is one parasite. To date, no infections in mice have resulted from inoculation of extraglandular parasites. Histological and dissection studies support both the classical route and an alternate route of infection development in flies. No SG-infected flies have been found which did not also have proventricular and anterior and posterior midgut (AMG and PMG) infections. Although the AMG is where the heaviest MG infections occur, the PMG seems to support the last survivors in a moribund MG infection. No parasites have been found in the hindgut.
- Subjects :
- Infectivity
Tsetse Flies
biology
Salivary gland
Trypanosoma brucei brucei
fungi
Tsetse fly
Hindgut
Midgut
Trypanosoma brucei rhodesiense
biology.organism_classification
medicine.disease
Virology
Salivary Glands
Mice
Infectious Diseases
medicine.anatomical_structure
medicine
Animals
Parasitology
African trypanosomiasis
Digestive System
Trypanosomiasis
Subjects
Details
- ISSN :
- 14761645 and 00029637
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- The American Journal of Tropical Medicine and Hygiene
- Accession number :
- edsair.doi.dedup.....b1f41624dfdeb1b803f6dd942c70a35b