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Complications of intrathecal baclofen pump treatment in children with spastic cerebral palsy. A comparative analysis of patients weighing over or under 20 kg at the time of implantation
- Source :
- Journal of pediatric orthopedics. Part B, Vol. 31, No 2 (2022) pp. 202-207
- Publication Year :
- 2022
-
Abstract
- Objective The purpose of this study was to investigate the incidence of complications in pediatric spastic cerebral palsy (CP) patients weighing less than 20 kg at the time of intrathecal baclofen (ITB) pump implantation and to compare it with spastic CP patients heavier than 20 kg. Material and methods Twenty-seven patients with spastic CP (14 males) treated with ITB implantation at our institution between January 2002 and January 2018 were retrospectively reviewed. Eight of the 27 patients had a bodyweight below 20 kg (group A) and 19 had weight above 20 kg (group B). Results Group A had a significantly more important proportion of patients with the Gross Motor Function Classification System V compared to group B (88 vs. 42%). The median follow-up was respectively 2.5 (1.8-4.6) and 4.6 (1.9-10.0) years in groups A and B. Median age at the time of ITB implantation was 7.4 (2.8-12.8) and 13.7 (6.5-16.8) years in groups A and B (P = 0.002). The proportion of patients with complications or reoperation was NS between groups A and B (P > 0.05). No postoperative infections were recorded in any of the groups. During follow-up, five patients died (63%) in group A and three (16%) in group B (P = 0.049) within 3.8 years on average after ITB implantation. Conclusions ITB therapy in spastic CP patients weighing less than 20 kg seems to be as well tolerated and effective as it is in heavier (>20 kg) pediatric patients.
- Subjects :
- Male
Baclofen
Group B
Spastic cerebral palsy
Spastic
medicine
Humans
Orthopedics and Sports Medicine
Child
Injections, Spinal
Retrospective Studies
ddc:618
Muscle Relaxants, Central
business.industry
Cerebral Palsy
Incidence (epidemiology)
Gross Motor Function Classification System
Pump
medicine.disease
Weight
Intrathecal baclofen
Muscle Spasticity
Anesthesia
Pediatrics, Perinatology and Child Health
Cerebral palsy
Lioresal
Spasticity
business
Subjects
Details
- Language :
- English
- ISSN :
- 1060152X
- Database :
- OpenAIRE
- Journal :
- Journal of pediatric orthopedics. Part B, Vol. 31, No 2 (2022) pp. 202-207
- Accession number :
- edsair.doi.dedup.....b1e03c1df4350d53602707f6ee009c6f