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Bio-synthesis of Barleria gibsoni leaf extract mediated zinc oxide nanoparticles and their formulation gel for wound therapy in nursing care of infants and children
- Source :
- Journal of photochemistry and photobiology. B, Biology. 189
- Publication Year :
- 2018
-
Abstract
- Bio-synthesis of nano-metal oxide particles is gaining lot of significance and recommended as promising substitute not only physical methods but also chemical methods. Here in, we demonstrate the nano-zinc oxide (nano-ZnO) particles were successfully prepared by an eco-friendly process using plant Barleria gibsoni (B. gibsoni) aqueous leaf extract. The water leaf extract of B. gibsoni responsible for not only reducing source but also protective agent. The prepared nano-ZnO particles were studied by UV–Vis diffuse reflectance (UV-DRS), Photoluminescence (PL), Fourier transform (FT-IR) infrared spectroscopy, X-ray diffraction spectroscopy (X-RD), transmission electron microscopy (TEM), thermal stability was studied by thermogravimetric and differential thermal (TG-DTA) analysis and particle size by zeta sizer, dynamic light scattering (DLS). UV-DRS spectrum of nano-ZnO particles showed below at wave length 400 nm. FT-IR spectra showed that plant metabolites like polyphenols, flavonoids and amino acids etc., are act as reducing and protective agent. X-RD studies revealed the formed nano-ZnO particles have hexagonal (wurtzite) structure. TEM analysis confirmed the range of nanoparticles between 30 and 80 nm, which is supported by DLS analysis. The antibacterial property of synthesized nano-ZnO particles was tested with bacterial pathogens showed good results. The developed nano-ZnO gel act as an efficient and superior another tropical antimicrobial formulations for healing of burn infections. Moreover, the formulated nano-ZnO gel exhibited a remarkable wound healing potential in rats.
- Subjects :
- Thermogravimetric analysis
Adolescent
Biophysics
Infrared spectroscopy
Nanoparticle
Metal Nanoparticles
02 engineering and technology
Microbial Sensitivity Tests
010402 general chemistry
01 natural sciences
Nursing care
Dynamic light scattering
Humans
Radiology, Nuclear Medicine and imaging
Thermal stability
Particle Size
Child
Wound Healing
Radiation
Aqueous solution
Radiological and Ultrasound Technology
Chemistry
Plant Extracts
technology, industry, and agriculture
Infant
021001 nanoscience & nanotechnology
0104 chemical sciences
Anti-Bacterial Agents
Plant Leaves
Child, Preschool
Particle size
Zinc Oxide
0210 nano-technology
Gels
Nuclear chemistry
Subjects
Details
- ISSN :
- 18732682
- Volume :
- 189
- Database :
- OpenAIRE
- Journal :
- Journal of photochemistry and photobiology. B, Biology
- Accession number :
- edsair.doi.dedup.....b1cf7ab10a50cf8464229dd22a008e4f