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Design optimisation of a TOF-based collimated camera prototype for online hadrontherapy monitoring

Authors :
J. Krimmer
Marco Pinto
F. Roellinghoff
Cédric Ray
Nicolas Freud
Etienne Testa
Denis Dauvergne
Jean Michel Létang
Institut de Physique Nucléaire de Lyon (IPNL)
Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL)
Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)
Imagerie Tomographique et Radiothérapie
Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS)
Université Jean Monnet [Saint-Étienne] (UJM)-Hospices Civils de Lyon (HCL)-Institut National des Sciences Appliquées de Lyon (INSA Lyon)
Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL)
Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-Hospices Civils de Lyon (HCL)-Institut National des Sciences Appliquées de Lyon (INSA Lyon)
Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Source :
Physics in Medicine and Biology, Physics in Medicine and Biology, IOP Publishing, 2014, 59 (24), pp.7653. ⟨10.1088/0031-9155/59/24/7653⟩
Publication Year :
2014
Publisher :
IOP Publishing, 2014.

Abstract

International audience; Hadrontherapy is an innovative radiation therapy modality for which one of the main key advantages is the target conformality allowed by the physical properties of ion species. However, in order to maximise the exploitation of its potentialities, online monitoring is required in order to assert the treatment quality, namely monitoring devices relying on the detection of secondary radiations. Herein is presented a method based on Monte Carlo simulations to optimise a multi-slit collimated camera employing time-of-flight selection of prompt-gamma rays to be used in a clinical scenario. In addition, an analytical tool is developed based on the Monte Carlo data to predict the expected precision for a given geometrical configuration. Such a method follows the clinical workflow requirements to simultaneously have a solution that is relatively accurate and fast. Two different camera designs are proposed, considering different endpoints based on the trade-off between camera detection efficiency and spatial resolution to be used in a proton therapy treatment with active dose delivery and assuming a homogeneous target.

Details

ISSN :
13616560 and 00319155
Volume :
59
Database :
OpenAIRE
Journal :
Physics in Medicine and Biology
Accession number :
edsair.doi.dedup.....b1a3d474856a21db486d7b0b2a575ea1