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Design optimisation of a TOF-based collimated camera prototype for online hadrontherapy monitoring
- Source :
- Physics in Medicine and Biology, Physics in Medicine and Biology, IOP Publishing, 2014, 59 (24), pp.7653. ⟨10.1088/0031-9155/59/24/7653⟩
- Publication Year :
- 2014
- Publisher :
- IOP Publishing, 2014.
-
Abstract
- International audience; Hadrontherapy is an innovative radiation therapy modality for which one of the main key advantages is the target conformality allowed by the physical properties of ion species. However, in order to maximise the exploitation of its potentialities, online monitoring is required in order to assert the treatment quality, namely monitoring devices relying on the detection of secondary radiations. Herein is presented a method based on Monte Carlo simulations to optimise a multi-slit collimated camera employing time-of-flight selection of prompt-gamma rays to be used in a clinical scenario. In addition, an analytical tool is developed based on the Monte Carlo data to predict the expected precision for a given geometrical configuration. Such a method follows the clinical workflow requirements to simultaneously have a solution that is relatively accurate and fast. Two different camera designs are proposed, considering different endpoints based on the trade-off between camera detection efficiency and spatial resolution to be used in a proton therapy treatment with active dose delivery and assuming a homogeneous target.
- Subjects :
- Computer science
medicine.medical_treatment
Physics::Medical Physics
Real-time computing
Monte Carlo method
Online Systems
Collimated light
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Proton Therapy
medicine
Humans
Polymethyl Methacrylate
Radiology, Nuclear Medicine and imaging
[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]
Radiometry
Proton therapy
Image resolution
Simulation
Modality (human–computer interaction)
Radiological and Ultrasound Technology
Phantoms, Imaging
Equipment Design
Radiotherapy, Computer-Assisted
Radiation therapy
Gamma Rays
Homogeneous
030220 oncology & carcinogenesis
[PHYS.PHYS.PHYS-MED-PH]Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph]
Key (cryptography)
Monte Carlo Method
Subjects
Details
- ISSN :
- 13616560 and 00319155
- Volume :
- 59
- Database :
- OpenAIRE
- Journal :
- Physics in Medicine and Biology
- Accession number :
- edsair.doi.dedup.....b1a3d474856a21db486d7b0b2a575ea1