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Quality of Life in Danish Patients with Multiple Myeloma during the COVID-19 Pandemic
- Source :
- Aarhus University, Redder, L, Møller, S, Johnsen, A T, Jarden, M, Andersen, C L, Jensen, B A, Frederiksen, H, Gregersen, H, Klostergaard, A, Steffensen, M S, Pedersen, P T, Hinge, M, Frederiksen, M, Helleberg, C, Mylin, A K, Abildgaard, N & Nielsen, L K 2021, ' Quality of Life in Danish Patients with Multiple Myeloma during the COVID-19 Pandemic ', COVID, vol. 1, no. 1, pp. 303-314 . https://doi.org/10.3390/covid1010024, Redder, L, Möller, S, Johnsen, A T, Jarden, M E, Andersen, C L, Jensen, B A, Frederiksen, H, Gregersen, H, Klostergaard, A, Steffensen, M S, Abildgaard, N & Kongsgaard Nielsen, L 2021, ' Quality of Life in Danish Patients with Multiple Myeloma during the COVID-19 Pandemic ', COVID, vol. 1, no. 1, pp. 303-314 . https://doi.org/10.3390/covid1010024, COVID, Volume 1, Issue 1, Pages 24-314, Redder, L, Möller, S, Johnsen, A T, Jarden, M, Amdi, B, Andersen, C L, Frederiksen, H, Gregersen, H, Klostergaard, A, Steffensen, M S, Pedersen, P T, Hinge, M, Frederiksen, M, Helleberg, C, Mylind, A K, Abildgaard, N & Nielsen, L K 2021, ' Quality of Life in Danish Patients with Multiple Myeloma during the COVID-19 pandemic ', Cancer .
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- In general, governments and health authorities have taken precautions during the COVID-19 pandemic to reduce the viral spread and protect vulnerable citizens. Patients with multiple myeloma (MM) have an increased risk of being infected with COVID-19 and developing a fatal course due to the related immunodeficiency. We investigated how Danish patients with MM reported their quality of life (QoL) pre-COVID and during COVID, in an ongoing longitudinal QoL survey. The responses given during the first and second wave of the COVID-19 pandemic were pooled, analyzed and compared to the same period the year before. We hypothesized that locking down the society would have caused deteriorated QoL and that patients living alone and those under the age of 65 would be particularly affected by the situation. Surprisingly, our study showed the opposite. Statistically significant and clinically relevant differences were primarily found during the first lock down and represented reduced fatigue, improved role functioning, decreased insomnia and improved physical health summaries in patients below 65 years of age. These results indicate that Danish patients with MM might have felt protected and safe by COVID restrictions. Otherwise, the questionaries used in QoL-MM survey may not have been able to capture the impact of the COVID-19 pandemic. Importantly, this indicates that QoL survey data obtained in clinical studies, in countries with highly developed health-care systems using standard questionnaires during the pandemic, allow room for interpretation without being adjusted for the impacts of the pandemic. In general, governments and health authorities have taken precautions during the COVID-19 pandemic to reduce the viral spread and protect vulnerable citizens. Patients with multiple myeloma (MM) have an increased risk of being infected with COVID-19 and developing a fatal course due to the related immunodeficiency. We investigated how Danish patients with MM reported their quality of life (QoL) pre-COVID and during COVID, in an ongoing longitudinal QoL survey. The responses given during the first and second wave of the COVID-19 pandemic were pooled, analyzed and compared to the same period the year before. We hypothesized that locking down the society would have caused deteriorated QoL and that patients living alone and those under the age of 65 would be particularly affected by the situation. Surprisingly, our study showed the opposite. Statistically significant and clinically relevant differences were primarily found during the first lock down and represented reduced fatigue, improved role functioning, decreased insomnia and improved physical health summaries in patients below 65 years of age. These results indicate that Danish patients with MM might have felt protected and safe by COVID restrictions. Otherwise, the questionaries used in QoL-MM survey may not have been able to capture the impact of the COVID-19 pandemic. Importantly, this indicates that QoL survey data obtained in clinical studies, in countries with highly developed health-care systems using standard questionnaires during the pandemic, allow room for interpretation without being adjusted for the impacts of the pandemic.
- Subjects :
- medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
business.industry
COVID-19 pandemic 4
EORTC QLQ-MY20 6
medicine.disease
language.human_language
multiple myeloma
Danish
SF12v2
quality of life
Quality of life
EORTC QLQ-CIPN20 7
Emergency medicine
Pandemic
EORTC QLQ-C30 5
medicine
language
General Earth and Planetary Sciences
Survey data collection
In patient
business
Immunodeficiency
Multiple myeloma
General Environmental Science
Subjects
Details
- ISSN :
- 26738112
- Volume :
- 1
- Database :
- OpenAIRE
- Journal :
- COVID
- Accession number :
- edsair.doi.dedup.....b1a2cd85a883041c6fbf67f703ee246e