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An individualized food-based nutrition intervention reduces visceral and total body fat while preserving skeletal muscle mass in breast cancer patients under antineoplastic treatment
- Source :
- Clinical Nutrition. 40:4394-4403
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Summary Background & aims Breast cancer patients (BCP) during treatment often experience an increase in body weight and fat mass, and a decrease in muscle mass known as sarcopenic obesity, affecting their prognosis and quality of life. We aimed to evaluate the effect of a 6-month individualized food-based nutrition intervention program in nonmetastatic BCP body composition during treatment. Methods This is a pre-post study in recently diagnosed women with invasive ductal/lobular breast carcinoma (clinical stage I-III). The individualized nutrition intervention was based on the dynamic macronutrient meal equivalent menu method (MEM). Dietary plans were developed according to WCRF/AICR guidelines, BCP total energy expenditure, 1.2–1.5 g/kgBW/d of protein intake, 5–9 servings/day of fruits and vegetables, and a caloric restriction (500–1000 kcal/d) when applicable (BMI ≥ 25 kg/m2). Follow-up was every 2-weeks and a different diet menu was provided in each session during 6 months. Baseline and final measurements included the assessment of anthropometry, body composition, and physical activity. Results Twenty-two participants completed the study and at diagnosis 68% were overweighed or obese. After the 6-month nutrition intervention program, BCP lost 3.1 kg (p Conclusions The individualized food-based nutrition intervention program empowered BCP to make informed healthy food choices within their personal preferences, socioeconomic and cultural background. With this type of intervention, nonmetastatic BCP reduced body weight, fat-mass, fat mass index, visceral and abdominal fat, while preserving skeletal muscle mass, during antineoplastic treatment. ClinicalTrials.gov NCT03625635 .
- Subjects :
- Adult
0301 basic medicine
medicine.medical_specialty
Lobular Breast Carcinoma
Nutritional Status
Adipose tissue
Breast Neoplasms
030209 endocrinology & metabolism
Intra-Abdominal Fat
Critical Care and Intensive Care Medicine
03 medical and health sciences
0302 clinical medicine
Breast cancer
Quality of life
Internal medicine
Vegetables
Humans
Medicine
Sarcopenic obesity
Stage (cooking)
Muscle, Skeletal
Caloric Restriction
Meal
030109 nutrition & dietetics
Nutrition and Dietetics
business.industry
Body Weight
Middle Aged
Anthropometry
medicine.disease
Adipose Tissue
Fruit
Body Composition
Female
Dietary Proteins
Nutrition Therapy
Diet, Healthy
Energy Metabolism
business
Subjects
Details
- ISSN :
- 02615614
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Clinical Nutrition
- Accession number :
- edsair.doi.dedup.....b1597fa43b2f860eb77f417c3209e712