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Rhodium(III)-Catalyzed Tandem [2+2+2] Annulation-Lactamization of Anilides with Two Alkynoates via Cleavage of Two Adjacent C−H or C−H/C−O bonds
- Source :
- Chemistry - An Asian Journal. 11:2260-2264
- Publication Year :
- 2016
- Publisher :
- Wiley, 2016.
-
Abstract
- An electron-deficient Cp(E) rhodium(III) complex bearing a cyclopentadienyl ligand with two ethyl ester substituents catalyzes the tandem [2+2+2] annulation-lactamization of acetanilides with two alkynoates via cleavage of adjacent two C-H bonds to give densely substituted benzo[cd]indolones. The reactions of meta-methoxy-substituted acetanilides with two alkynoates also provided benzo[cd]indolones via cleavage of adjacent C-H/C-O bonds. Furthermore, 3,5-dimethoxyacetanilides reacted with two alkynoates to give dearomatized spiro compounds.
- Subjects :
- Annulation
Tandem
010405 organic chemistry
Ligand
Stereochemistry
Organic Chemistry
chemistry.chemical_element
General Chemistry
010402 general chemistry
Cleavage (embryo)
01 natural sciences
Biochemistry
0104 chemical sciences
Rhodium
Catalysis
chemistry.chemical_compound
chemistry
Cyclopentadienyl complex
Acetanilide
Subjects
Details
- ISSN :
- 18614728
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Chemistry - An Asian Journal
- Accession number :
- edsair.doi.dedup.....b12b5337dc8f192e6323ed4b248a5d90