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Population-based BRCA1/BRCA2 screening in Ashkenazi Jews: a call for evidence
- Source :
- Genetics in medicine : official journal of the American College of Medical Genetics. 11(9)
- Publication Year :
- 2009
-
Abstract
- testing in the Ashkenazi Jewish population,aimed at reducing morbidity and mortality of breast/ovariancancer, is seemingly an obvious candidate for such a screeningprogram. In Ashkenazi Jews, three common, easily tested mu-tations account for the majority of deleterious alleles, effectivepreventive measures for
- Subjects :
- congenital, hereditary, and neonatal diseases and abnormalities
endocrine system diseases
Population
Breast Neoplasms
Population based
Brca1 brca2
Medicine
Humans
Ashkenazi Jewish
Genetic Predisposition to Disease
Genetic Testing
skin and connective tissue diseases
education
Genetics (clinical)
Genetics
BRCA2 Protein
Ovarian Neoplasms
education.field_of_study
business.industry
BRCA1 Protein
nutritional and metabolic diseases
Ashkenazi jews
Deleterious alleles
Jews
Female
business
Medical genetics of Jews
Demography
Subjects
Details
- ISSN :
- 15300366
- Volume :
- 11
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Genetics in medicine : official journal of the American College of Medical Genetics
- Accession number :
- edsair.doi.dedup.....b129ce2a751622b40041827fe2e83f23