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Cost-Effectiveness of Screening Helicobacter pylori for Gastric Cancer Prevention: a Systematic Review
- Source :
- Journal of Gastrointestinal Cancer. 53:1093-1103
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Globally, prevalence of Helicobacter pylori is around 50%, and it has a directly proportional relationship with gastric cancer. Screening and treatment of Helicobacter pylori could reduce gastric cancer by 35%. Drawing on the scarce resources, it is reasonable to use the most cost-effectiveness Helicobacter pylori screening procedure. The purpose of this study was to evaluate Helicobacter pylori screening techniques and to specify the efficient technique from a cost-effectiveness perspective. This systematic review was conducted via searching electronic databases including Scopus, Embase, PubMed, Web of Science, and Cochrane Reviews. Our search retrieved 904 articles, of which, 606 full-text studies have been selected after duplicate removal. Next, the 25 articles were sorted based on eligibility criteria and quality appraisal; eventually, only eight studies have been included for analysis. We reported the incremental cost-effectiveness ratio (ICER) screening compared to non-screening and different screening strategies. Eight studies were identified and retained for the final analysis. In this study, when screening techniques were compared to no-screening, serology screening techniques showed to be cost-effective. The lowest ICER calculated was US$$1230 cost per life-year gained (LYG) and US$1500 cost per quality-adjusted life-year (QALY). However, determining the optimal strategy compared to other strategies was depended on parameters such as context-specific, type of cost, threshold, and perspective, and also, it influenced by the framework of the cost-effectiveness analysis.
- Subjects :
- medicine.medical_specialty
Screening techniques
Cost effectiveness
Cost-Benefit Analysis
Scopus
Helicobacter Infections
Quality appraisal
Stomach Neoplasms
Internal medicine
medicine
Humans
Mass Screening
Early Detection of Cancer
health care economics and organizations
Helicobacter pylori
biology
Gastric cancer prevention
business.industry
Gastroenterology
Cancer
biology.organism_classification
medicine.disease
Oncology
business
Incremental cost-effectiveness ratio
Subjects
Details
- ISSN :
- 19416636 and 19416628
- Volume :
- 53
- Database :
- OpenAIRE
- Journal :
- Journal of Gastrointestinal Cancer
- Accession number :
- edsair.doi.dedup.....b0f23d737d018590d75a233ec7bfc628