Pyrimido[4,5-d]pyrimidin-4(1H)-one derivatives as selective inhibitors of EGFR threonine790 to methionine790 (T790M) mutants

Subjects

Subjects :

ErbB Receptors
Threonine
T790M
Methionine
Stereochemistry
Chemistry
Drug Design
Mutant
General Chemistry
Selectivity
Combinatorial chemistry
Catalysis
Cell Proliferation

Details

ISSN :

15213773

Volume :

52

Issue :

32

Database :

OpenAIRE

Journal :

Angewandte Chemie (International ed. in English)

Accession number :

edsair.doi.dedup.....b0f0a5e5921f23d2d97e4d32eaedf48d