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A Swine Model of Filter-Assisted Caval Thrombosis for Endovascular Thrombectomy Using AngioJet
- Source :
- Journal of cardiovascular translational research. 14(2)
- Publication Year :
- 2020
-
Abstract
- To assess the feasibility of creating swine model of filter-assisted caval thrombosis and to evaluate the efficacy in removing clot in this model using rheolytic thrombectomy. The model was created by implanting a filter into the inferior vena cava followed by injection of autologous thrombus. Rheolytic thrombectomy was performed for all models to remove the clot. The success rate of model creation and the efficacy of clot removal were analyzed. The success rate of model creation was 100% (15/15). Following rheolytic thrombectomy, 3 of 5 pigs attained complete clot removal in a 7-day-old model, while no pigs attained complete clot removal in 14- and 21-day-old models. Creating a filter-related caval thrombosis model in swine is technically feasible and can be used to mimic a clinical episode of caval thrombosis from acute phase to chronic occlusion. Rheolytic thrombectomy can be used to remove filter-related thrombosis that aged less than 14 days. Graphical Abstract Swine Model of Filter-Assisted Caval Thrombotic Occlusion.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Time Factors
Vena Cava Filters
Sus scrofa
Pharmaceutical Science
Vena Cava, Inferior
030204 cardiovascular system & hematology
Inferior vena cava
03 medical and health sciences
0302 clinical medicine
Animal model
Genetics
medicine
Animals
Thrombus
Genetics (clinical)
Thrombectomy
Venous Thrombosis
Chronic occlusion
business.industry
Endovascular Procedures
Phlebography
medicine.disease
Thrombosis
Surgery
Disease Models, Animal
030104 developmental biology
medicine.vein
cardiovascular system
Molecular Medicine
Feasibility Studies
Cardiology and Cardiovascular Medicine
business
circulatory and respiratory physiology
Subjects
Details
- ISSN :
- 19375395
- Volume :
- 14
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of cardiovascular translational research
- Accession number :
- edsair.doi.dedup.....b08dd29f6bcabd3a7e6e249f09ec26fd