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WormBase: a modern Model Organism Information Resource

Authors :
Christian A. Grove
Faye H. Rodgers
Gary Williams
Wen J. Chen
Jaehyoung Cho
Paul W. Sternberg
Karen Yook
Valerio Arnaboldi
Matthew Russell
Sibyl Gao
Lincoln Stein
Raymond Lee
Qinghua Wang
Juancarlos Chan
Paul Davis
Paulo A. S. Nuin
Daniela Raciti
Michael Paulini
Adam Wright
Kevin L. Howe
Gary Schindelman
Hans-Michael Müller
Scott Cain
Tim Schedl
Cecilia Nakamura
Ranjana Kishore
Kimberly Van Auken
Todd W. Harris
Source :
Nucleic Acids Research
Publication Year :
2019

Abstract

WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary facets: curation, user interface and architecture. In this update, we describe progress in each of these three areas. In particular, we discuss the status of literature curation and recently added data, detail new features of the web interface and options for users wishing to conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture by leveraging commercial cloud offerings. We conclude with a description of WormBase's role as a founding member of the nascent Alliance of Genome Resources.

Details

ISSN :
13624962
Volume :
48
Issue :
D1
Database :
OpenAIRE
Journal :
Nucleic acids research
Accession number :
edsair.doi.dedup.....b08bc22353342432a0cac09b572e55b0