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Incidence of Venous Thromboembolism and Mortality in Patients with Initial Presentation of COVID-19
- Source :
- Journal of Thrombosis and Thrombolysis
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Venous thromboembolism (VTE) has emerged as an important issue in patients with COVID-19. The purpose of this study is to identify the incidence of VTE and mortality in COVID-19 patients initially presenting to a large health system. Our retrospective study included adult patients (excluding patients presenting with obstetric/gynecologic conditions) across a multihospital health system in the New York Metropolitan Region from March 1-April 27, 2020. VTE and mortality rates within 8 h of assessment were described. In 10,871 adults with COVID-19, 118 patients (1.09%) were diagnosed with symptomatic VTE (101 pulmonary embolism, 17 deep vein thrombosis events) and 28 patients (0.26%) died during initial assessment. Among these 146 patients, 64.4% were males, 56.8% were 60 years or older, 15.1% had a BMI > 35, and 11.6% were admitted to the intensive care unit. Comorbidities included hypertension (46.6%), diabetes (24.7%), hyperlipidemia (14.4%), chronic lung disease (12.3%), coronary artery disease (11.0%), and prior VTE (7.5%). Key medications included corticosteroids (22.6%), statins (21.2%), antiplatelets (20.6%), and anticoagulants (20.6%). Highest D-Dimer was greater than six times the upper limit of normal in 51.4%. Statin and antiplatelet use were associated with decreased VTE or mortality (each p
- Subjects :
- Male
medicine.medical_specialty
Deep vein
New York
030204 cardiovascular system & hematology
Article
law.invention
Fibrin Fibrinogen Degradation Products
03 medical and health sciences
0302 clinical medicine
Risk Factors
law
Internal medicine
medicine
Humans
cardiovascular diseases
030212 general & internal medicine
Mortality
Retrospective Studies
Venous Thrombosis
SARS-CoV-2
business.industry
Incidence
Mortality rate
Incidence (epidemiology)
COVID-19
Outpatient
Thrombosis
Retrospective cohort study
Hematology
Middle Aged
Protective Factors
medicine.disease
Intensive care unit
Pulmonary embolism
Intensive Care Units
Venous thrombosis
Outcome and Process Assessment, Health Care
medicine.anatomical_structure
Female
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Pulmonary Embolism
Cardiology and Cardiovascular Medicine
business
Platelet Aggregation Inhibitors
Venous thromboembolism
Subjects
Details
- ISSN :
- 1573742X and 09295305
- Volume :
- 51
- Database :
- OpenAIRE
- Journal :
- Journal of Thrombosis and Thrombolysis
- Accession number :
- edsair.doi.dedup.....b0578c1b248a9906847e9e3050e67617