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Cardiac autoimmunity in HIV related heart muscle disease
- Source :
- Heart. 79:599-604
- Publication Year :
- 1998
- Publisher :
- BMJ, 1998.
-
Abstract
- Objective—To assess the frequency of circulating cardiac specific autoantibodies in HIV positive patients with and without echocardiographic evidence of left ventricular dysfunction. Subjects—74 HIV positive patients including 28 with echocardiographic evidence of heart muscle disease, 52 HIV negative people at low risk of HIV infection, and 14 HIV negative drug users who had all undergone non-invasive cardiac assessment were studied along with a group of 200 healthy blood donors. Results—Cardiac autoantibodies detected by indirect immunofluorescence (serum dilution 1/10) were more common in the HIV positive patients (15%), particularly the HIV heart muscle disease group (21%), than in HIV negative controls (3.5%) (both p
- Subjects :
- Adult
Cardiomyopathy, Dilated
Male
medicine.medical_specialty
Myocarditis
Heart Diseases
Heart disease
Cardiomyopathy
Enzyme-Linked Immunosorbent Assay
Myosins
Gastroenterology
Statistics, Nonparametric
Ventricular Dysfunction, Left
Acquired immunodeficiency syndrome (AIDS)
HIV Seronegativity
Internal medicine
HIV Seropositivity
Idiopathic dilated cardiomyopathy
medicine
Humans
Fluorescent Antibody Technique, Indirect
Autoantibodies
Analysis of Variance
business.industry
Autoantibody
virus diseases
Dilated cardiomyopathy
medicine.disease
CD4 Lymphocyte Count
Echocardiography
Case-Control Studies
Papers
Immunology
Female
Cardiology and Cardiovascular Medicine
business
Biomarkers
Subjects
Details
- ISSN :
- 13556037
- Volume :
- 79
- Database :
- OpenAIRE
- Journal :
- Heart
- Accession number :
- edsair.doi.dedup.....afb40df5958d1350ce8cb9a1ceb5d2ad