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Larval nutritional stress affects vector life history traits and human malaria transmission
- Source :
- Scientific Reports, Scientific Reports, Nature Publishing Group, 2016, 6, pp.36778. ⟨10.1038/srep36778⟩, Scientific Reports, 2016, 6, pp.36778. ⟨10.1038/srep36778⟩
- Publication Year :
- 2016
- Publisher :
- HAL CCSD, 2016.
-
Abstract
- Exposure to stress during an insect’s larval development can have carry-over effects on adult life history traits and susceptibility to pathogens. We investigated the effects of larval nutritional stress for the first time using field mosquito vectors and malaria parasites. In contrast to previous studies, we show that larval nutritional stress may affect human to mosquito transmission antagonistically: nutritionally deprived larvae showed lower parasite prevalence for only one gametocyte carrier; they also had lower fecundity. However, they had greater survival rates that were even higher when infected. When combining these opposing effects into epidemiological models, we show that larval nutritional stress induced a decrease in malaria transmission at low mosquito densities and an increase in transmission at high mosquito densities, whereas transmission by mosquitoes from well-fed larvae was stable. Our work underscores the importance of including environmental stressors towards understanding host–parasite dynamics to improve disease transmission models and control.
- Subjects :
- 0301 basic medicine
media_common.quotation_subject
[SDV]Life Sciences [q-bio]
Plasmodium falciparum
Zoology
Insect
MESH: Insect Vectors
Biology
Article
law.invention
Life history theory
03 medical and health sciences
MESH: Plasmodium falciparum/growth & development
law
Stress, Physiological
Anopheles
parasitic diseases
medicine
Gametocyte
Animals
Humans
MESH: Animals
MESH: Stress, Physiological
Life History Traits
media_common
Larva
Multidisciplinary
MESH: Humans
MESH: Life History Traits
MESH: Anopheles/parasitology
Ecology
fungi
MESH: Anopheles/growth & development
medicine.disease
Fecundity
3. Good health
Insect Vectors
Malaria
MESH: Larva/parasitology
MESH: Malaria/transmission
030104 developmental biology
Transmission (mechanics)
MESH: Larva/growth & development
Vector (epidemiology)
Female
MESH: Female
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Database :
- OpenAIRE
- Journal :
- Scientific Reports, Scientific Reports, Nature Publishing Group, 2016, 6, pp.36778. ⟨10.1038/srep36778⟩, Scientific Reports, 2016, 6, pp.36778. ⟨10.1038/srep36778⟩
- Accession number :
- edsair.doi.dedup.....af95acecfb6d557677e6fe1f626f56f4