Anticancer effect of purified polysaccharide from marine clam Donax variabilis on A549 cells

Authors :: Arulvasu Chinnasamy
Gracy Jenifer Sahayanathan
Deepakrajasekar Padmanaban
Kavitha Raja
Source :: Journal of Food Biochemistry. 44
Publication Year :: 2020
Publisher :: Hindawi Limited, 2020.
Abstract: The marine invertebrates are one of the main leads to the derivation of anticancer compounds. The present investigation was to explore the anticancer effect of a potentially active polysaccharide fraction from marine clam Donax variabilis on human lung cancer cells (A549). A polysaccharide was purified from the whole tissue of D. variabilis by GFC and characterized by FT-IR and NMR spectroscopy. Subsequently, fraction 2.1 (F2.1) showed a significant inhibitory effect on A549 cells (p

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